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Strange or interesting information and facts:

New Dangers From Diet Colas?

  Occasionally I like to have a Diet Coke. I know that aspartame is bad, but the other day I noticed the words "Phenylketonurics: Contains Phenylalanine" on the label. What is this? And why does Coke see fit to print it in the old "saccharine" manner? This raises my suspicions.

There's no reason for most people to worry about phenylalanine. The warning you've seen is aimed at people with phenylketonuria (PKU), an inherited disorder in which the enzyme that converts the amino acid phenylalanine into another amino acid, tyrosine, is defective. If undetected, PKU can lead to severe mental retardation and developmental problems in children. Fortunately, there's a screening test administered shortly after birth that detects the 1 in 16,000 newborns with the condition.

Being phenylketonuric requires that you maintain a diet free of phenylalanine. This isn't so hard during infancy as there's special formula to replace regular formulas and mother's milk, both rich in phenylalanine. The difficulty comes later because phenylalanine is a natural component of most foods containing protein and can turn up anywhere, even, as you noticed, in diet cola. Consequently, the only regular foods people with PKU can eat safely are vegetables.

There's some controversy over when, if ever, people with PKU can stop being mostly vegetarian and switch to a diet higher in protein. Some doctors feel that by 10 or 12 years old, most children with PKU can safely switch to a normal diet. I'm not one of them.

Recent evidence suggests that some adults with PKU develop Alzheimer's-like symptoms when they eat typical diets. Then, when they resume the low protein regime, symptoms vanish and normal intellectual capacity resumes. Because PKU can pass from mother to child and lead to irreversible brain damage as early as the first days after conception, it's vital for women with the disorder to keep a very low protein diet whenever there's a chance of becoming pregnant.

That's a long answer to your question, and probably one you didn't expect. The short answer is that phenylalanine in diet soft drinks won't hurt you, but the aspartame (NutraSweet) may be a different story.

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